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studies on cbd and alzheimer’s

The World Health Organization (WHO) stated that “no public health problems… have been associated with the use of pure CBD,” and there has been no known association with potential for dependence or abuse, unlike most pharma alternatives. The most commonly reported potential side effects of CBD usage were diarrhea and bloating, with some also reporting nausea. About 3% of patients in studies reported liver problems and had to discontinue CBD use. Specifically, in dementia, some patients reported increased tremor with high doses of CBD. As with any new treatment, patients and caregivers should monitor effects and outcomes closely.

Laws by State
CBD and medical cannabis is legally available to all adult users (21+) in Alaska, Arizona, California, Colorado, District of Columbia, Illinois, Maine, Massachusetts, Michigan, Nevada, New Jersey, Oregon, Vermont, and Washington. Legally recognized state ID is required for purchase.

What is CBG? (CBG vs. CBD)

Does Medicare cover CBD? Because of the federal prohibitions on prescribing Schedule 1 substances, there is no Medicare coverage for the purchase of medical marijuana or CBD derivatives. Any out-of-pocket costs one would incur purchasing marijuana for medical use will not count toward any deductibles under Part B or a Medicare Prescription Drug Plan.

Another cannabinoid (compound in cannabis) that has shown health benefits is cannabigerol, also known as CBG. Often taken as an oil, like CBD, CBG is rarer than CBD and THC because there is much less of it in a plant. Whereas cannabis strains usually contain about 25% THC and 20% CBD, the compound CBG makes up only about 1% of most plants. CBG can, however, be extracted at higher volumes if the plants are harvested at the right age, meaning younger. CBG turns into CBD and THC as the plant gets older.

Forms of CBD Administration

2) CBD is a sedative and reduces awareness or alertness
Even in high doses (600mg), CBD has not produced sedating effects in healthy humans. CBD usually makes humans feel more awake and alert without negative impact on sleeping patterns. What is more likely happening is that cannabis strains being used by a patient that have high levels of CBD also contain a potentially sedating natural oil (terpene) such as myrcene.

Studies on cbd and alzheimer's

Molecular Targets in Rheumatoid Arthritis

This study searched publications, which were registered to databases or published by Aug 22, 2019, and targeted the full-text or abstracts of these publications. We selected the final nine studies met all selection criteria.

2.1. Search Method

Two in-vitro studies using CBD treated the right dorsal hippocampus of mice with human Aβ (1–42) peptide and applied CBD to evaluate the effects of CBD on neurotoxicity and inflammation. The results showed that CBD significantly inhibited the expression of GFAP, mRNA, and protein and reduced the expression of iNOS and IL-1β protein.19) Moreover, the effects of CBD were confirmed with and without the antagonist of PPARγ [20]. It was found that the blocking of PPARγ mitigated the effects of CBD on neural damage and CBD stimulated the neurogenesis of the hippocampus through interactions [20].

Methods

Therefore, we conducted this study to provide a basis for the treatment of dementia using cannabis, which is currently illegal in South Korea but known to be effective against neuroinflammation, while an effective method is needed for treating dementia, which is gradually becoming a social problem.