There are public health concerns about the safety of driving under the influence of medical marijuana. A JAMA study found lower rates of opioid overdose deaths in states with legal medical marijuana.
Murnion, B. “Medical Cannabis.” Aust Prescr. 2015 Dec; 38(6): 212–215.
Trending on MedicineNet
THC or tetrahydrocannabinol is the psychoactive compound in marijuana. It is responsible for the "high" people feel. There are two man-made drugs called dronabinol (Marinol) and nabilone (Cesamet) that are synthetic forms of THC. They are FDA-approved to prevent nausea and vomiting in people receiving chemotherapy.
Medical marijuana is the medical use of the Cannabis sativa or Cannabis indica plant to relieve symptoms of or treat diseases and conditions. The Cannabis plant was used medically for centuries around the world until the early 1900s. Medical marijuana facts can be difficult to find because strong opinions exist, both pros and cons. Medical uses and emerging research on off-label uses are summarized in this article.
What research is being done for medical marijuana?
There are over 60 peer-reviewed research studies examining the benefits of medical marijuana. Sixty-eight percent of these studies found benefit while 8% found no benefit. Twenty-three percent of the studies were inconclusive or neutral. Most research has been conducted on the compound CBD. The benefits of medical marijuana can be attributed to binding to the endocannabinoid system. This has many effects including
A. Cannabis is a plant of the Cannabaceae family and contains more than eighty biologically active chemical compounds. The most commonly known compounds are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Parts of the Cannabis sativa plant have been controlled under the Controlled Substances Act (CSA) since 1970 under the drug class “Marihuana” (commonly referred to as “marijuana”) [21 U.S.C. 802(16)]. “Marihuana” is listed in Schedule I of the CSA due to its high potential for abuse, which is attributable in large part to the psychoactive effects of THC, and the absence of a currently accepted medical use of the plant in the United States.
17. Does the FDA object to the clinical investigation of cannabis for medical use?
Research and Expanded Access
A. The Animal Medicinal Drug Use Clarification Act of 1994 (AMDUCA), permits veterinarians to prescribe extralabel uses of approved human and animal drugs for animals under certain conditions. Extralabel use must comply with all the provisions of AMDUCA and its implementing regulation at 21 CFR § 530. Among other limitations, these provisions allow extralabel use of a drug only on the lawful order of a licensed veterinarian in the context of a valid veterinarian-client-patient relationship and only in circumstances when the health of an animal is threatened or suffering, or death may result from failure to treat.