The hemp essential oil is a complex mixture of many volatile compounds, mainly monoterpenes, sesquiterpenes, and other terpenoid-like substances . The main chemical components are myrcene, β-caryophyllene, limonene, α-pinene, β-pinene, terpinolene, and α-humulene. The general properties of these substances include antidepressant, relaxant, anxiolytic, sedative, antimicrobial, and antioxidants . Some researchers studied the antibacterial properties of this oil. These findings show that industrial hemp EOs exhibited good antimicrobial activities, with respect to Gram (+) bacteria such as Enterococcus hirae, Enterococcus faecium, and S. salivarius subsp. thermophilus and against clostridia (in this case only C. sativa L. varieties Futura) . The study of Russo describes pharmacological properties of main terpenoids present in industrial hemp EOs .
In the research by Bahia et al., they reported that β-caryophyllene may be useful in treating anxiety and depression. Moreover they demonstrated the effect of β-caryophyllene and its underlying mechanism in a CB2 receptor-dependent manner in mice . These β-caryophyllene’s properties may explain why Cannabis users often cite relief of anxiety and depression as reason for their use. But, presently, the effects of hemp EOs inhalation on the brain in humans have not been studied and there are no studies on the possible therapeutic use. However, these studies support that hemp EOs inhalation can have a relaxing effect on the nervous system. Thus, this study is the first to focus on aspects such as brain wave activity and ANS parameters such as heart rate, blood pressure, respiratory rate, and skin temperature, as well as the assessment of mood states through comparative measures. Moreover gas chromatography characterization of hemp EOs was conducted.
2. Materials and Methods
Hexane used for preparing working solution was purchased from Carlo Erba (Rodano, MI, Italy), while the linear n-hydrocarbons (C9–C40) were purchased from Sigma-Aldrich.
2.1. Essential Oil Analysis
Percentages are obtained by FID peak-area normalization, all relative response factors being take as one (HP-5) column. Mean of three analyses. ∧ Linear retention indices (HP-5 column) relative to the series of n-hydrocarbons.
“The Controlled Substances Act (CSA) places all substances . . . regulated under existing federal law into one of five schedules. This placement is based upon the substance’s medical use, potential for abuse, and safety or dependence liability.” 10
The Food and Drug Administration (FDA) is responsible for reviewing and approving applications to ensure that new drugs meet the standards of the Food, Drug, and Cosmetic Act (FD&C Act).
Perhaps you have heard CBD called a cannabinoid. The term cannabinoid refers to any compound that triggers your endocannabinoid system by activating its receptors. Cannabinoids are produced naturally in your body, but they can also come from other sources.
“[Marijuana] is listed in Schedule I of the CSA due to its high potential for abuse, which is attributable in large part to the psychoactive effects of THC, and the absence of a currently accepted medical use of the plant in the United States.” 11 (Exceptions 12 )
Drug Approval Process of Schedule I Substances
All doTERRA essential oils, including Copaiba, are CPTG Certified Pure Tested Grade. This means that the oil is pure: there are no added fillers, synthetic ingredients, or harmful contaminants that would reduce its efficacy. Each batch of oil undergoes rigorous internal and third party testing to confirm that oils are meeting our quality standards. Every bottle of oil has a unique Quality ID that you can use to view the GC/MS test results from an independent, verified third party lab on Source to You.