Things that impact our metabolism include age, genetics, digestive system health, and lifestyle.
This involves absorption through the skin, and common products include balms, creams, gels, and patches. It is the slowest acting method, and it can take up to 45 minutes to work. On the plus side, it is a good option to tackle localized pain, especially if you experience side effects when using other forms.
Yet, the researchers also found that the effects seem to have a ceiling in doses between 400mg and 800mg. This is possibly because tissues become saturated and can’t absorb any more CBD.
As you have discovered, there isn’t one answer that tells you how long CBD takes to work. How well CBD affects you depends on the product’s quality, not to mention your body composition, physical size, and physical condition.
When it comes to CBD absorption, size matters. A heavier individual may need more CBD to have the same effect as a lighter person who uses a lower dose. Reasons for this could be related to the strength of blood flow, fat stores, and more. While cannabidiol dosing guidelines are always broad, you’ll have to take into account your own body weight.
Individuals with certain medical conditions may not process substances as well as healthier people. However, when it comes to CBD, a lack of homeostasis, or balance, in the ECS may speed up the rate of absorption.
According to this study, CBD reaches the general circulation and remains there longer in people with liver impairment than without.
This means that how CBD is absorbed is VERY important. Effective forms of CBD consumption not only get to the bloodstream faster, but they maintain substantial levels of the compound throughout the body. In other words, they offer high bioavailability. Additionally, the best ways to consume CBD involve bypassing the digestive system and metabolic process in the liver.
If you don’t want to vape your CBD, sublingual consumption is the next best option. It involves placing drops of CBD oil beneath the tongue. Generally, it’s recommended to hold the oil there for up to 60 seconds for the best absorption.
The method of consumption plays a critical role in how long it will take to feel the effects of CBD. CBD is available in many different forms, and each has an influence on the onset time, among other factors.
Administering a couple of drops of CBD oil directly under the tongue is the quickest and easiest way to reap the potential benefits. Photo by: Gina Coleman/Weedmaps
CBD interacts with the brain and body through a number of mechanisms. Upon ingestion, CBD interacts with a wide range of proteins in the body and central nervous system. A key part of this interaction takes place within the endocannabinoid system (ECS) — specifically the CB1 and CB2 cannabinoid receptors.