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how do you make cbd water soluble

How do you make cbd water soluble

Besides being water-compatible and easily mixed into beverages at essentially any desired concentrations, cannabis extract nanoemulsions (nano-cannabinoids) provide exceptionally high bioavailability and therapeutic effect, and are absorbed by the body, either orally or through the skin, very rapidly and completely. The uptake starts to occur in the mouth almost immediately upon oral administration. This means higher potency and faster onset of action for lower doses.

Both micro- and nanoemulsions can be prepared in concentrated forms that are fully miscible with water and, therefore, appear water-soluble. Both require the use of surfactants, which dilute the products, but are not otherwise a major concern, since several natural options are available with minimal negative effects. It is, of course, beneficial to use as little surfactants as possible. This is where nanoemulsions have a clear advantage: the amounts of surfactants used for their preparation are up to 10 times lower that those needed to make microemulsions.

CBD, THC and many other oils can, however, be made water compatible if they are formulated as micro– or nanoemulsions, which are stable and visually homogeneous oil/water mixtures. The definitions of these emulsion types, important differences between them and methods by which they can be prepared are provided in our earlier blog post: “Achieving Stability of Oil-in-Water and Water-in-Oil Emulsion Products” as well as in this free eBook:

Benefits of CBD and THC Nanoemulsions

Cannabinoids (CBD, THC, etc.) are hydrophobic (water-hating) oily substances and, as such, not water-soluble. They can, however, be formulated to be water-compatible and appear water-soluble.

Further information on CBD and THC nanoemulsions, including how they can be prepared using ultrasonic liquid processors, is provided in our recent blog post: “Are Cannabinoids More Effective in Nano Form?

The term “water-soluble CBD” has lately been extensively used throughout the medical cannabis industry. “Water-soluble” means able to homogeneously incorporate into water by separating into molecules or ions (dissolve like sugar, alcohol or salt). Oily substances, however, are repelled by water, which forces them to stay separate from it.

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How do you make cbd water soluble

A high-quality water-soluble CBD will have the following qualities that will benefit the product producer and the consumer.

Agglomerated Powder, which SōRSE has offered since 2019, allows for rapid hydration when dropped into liquid. That makes it the best solution for ready-to-make beverages like stick-packs.

In contrast, the body is more able to process and absorb water-soluble CBD because the oil, which is embedded in the emulsion, is recognized by the body as hydrophilic, or water-friendly. Emulsion technology breaks the oil down into small particle sizes for even dispersion and stability, which allows for greater absorption in the intestinal tract. This means that consumers experience the effects of water-soluble CBD between 10 and 20 minutes after ingestion.

An easy way to think about how emulsions behave is to imagine dropping food coloring into a glass of water. The color will eventually disperse evenly and completely transform the color of the water. (See video below)

How to Use Water-Soluble CBD

Many consumers ingest water-soluble CBD orally, via products like beverages, edibles, capsules, tablets, or powders. When choosing between an edible like a brownie and a beverage, it’s important to know that the onset times can be very different given the amount of fat in the edible. As mentioned earlier, it takes longer for the body to process fat, which means that it may take longer for the consumer to feel the CBD’s effects after eating the brownie than they would if they had consumed a beverage.

To understand the benefits water-soluble CBD in the form of an emulsion delivers, it’s important to explain how the body processes oil extracts first. When an oil-based cannabinoid is ingested, its bioavailability is limited because the oil is hydrophobic, meaning that it is incompatible with or insoluble in water. This means that the human body, which is over 60% water, has difficulty absorbing and processing the oil.

If the cannabinoids were left in their-oil based state and a beverage product developer tried to add that oil to water, the oil would rise to the top. Not only would the first sip be a less than appealing one, but the cannabinoids would not be evenly dispersed throughout the beverage, which is an important factor to consider for a safe, consistent experience.

Method #4: Water-Soluble Emulsions

Simply put, water-soluble CBD is CBD that can be dispersed in water and other liquids. When extracted from the hemp or cannabis plant, CBD and other cannabinoids are oils, which can be challenging to work with in terms of the sensory profile, dosage control, reliable and repeatable onset and duration, manufacturing, and labelling.

Liquid is ideal for ready-to-drink beverages and personal care items.

How do you make cbd water soluble

Precision manufactures and distributes the best extraction and post-processing equipment on the market for ethanol and hydrocarbon extraction. More award-winning concentrates are made with Precision extraction equipment than any other brand.

When processed using nanoemulsion, water-soluble CBD and THC can be absorbed more efficiently than traditional edibles. Due to this quick absorption process, consumers only have to wait minutes to feel “high,” instead of 30 minutes or over an hour for most edibles. This can help avoid overuse due to more prolonged effect onset timelines.

Diving into the water-soluble cannabinoid arena may be a solid business decision for some processors, but the effort comes with its challenges.

The equipment required to further process distillate or isolate into a water-soluble cannabinoid is relatively inexpensive. The biggest investment you’ll need to make is hiring highly-experienced staff and the R&D for your product formulation.

Getting Professional Advice

Suppose you’re considering diving into processing for water-soluble cannabinoids. In that case, one of the best things you can do is consult with at least a few industry experts who have experience with water-soluble cannabinoids. Labs that aren’t familiar with them may not completely understand what it takes to process, measure, and deliver the highest quality product, leading you down a path you don’t want to take. With the volatile nature of the cannabis industry, planning strategically and thoughtfully is always the best way to proceed.

According to Cannabis Tech, “Fortune Business Insights puts the cannabis beverage market at $8.521 million by 2027. The expected explosion of this product segment is thanks to rising consumer demand for non-smokable solutions, continued growth in the CBD market, and investments by several multinational beverage makers.”

While there are certainly hurdles to overcome in making water-soluble cannabinoids, there’s good news for cannabis processors. If you have the extraction and post-processing equipment to make THC distillate or CBD distillate and isolate, you already have the majority of the tools you need. Water-soluble cannabinoids can be created using a variety of solvent-based extraction methods, including ethanol, hydrocarbon or CO2 extraction.

The Technology Behind Water Soluble Cannabinoids

A continuing trend toward goal-oriented healthy living has led to a sharp decrease in alcohol consumption and a corresponding increase in sales of low-alcohol or non-alcoholic drinks. So much so that major breweries and distilleries are now investing in alternative products like cannabis-infused beverages.

Creating water-soluble cannabinoids also requires the use of an emulsifier, which forces two typically incompatible substances (such as oil and water) to mix. The nanoparticle cannabinoids need to pair up with water-friendly molecules (emulsifiers) to mix and stay suspended in a liquid. The challenge is finding a suitable emulsifier that helps two liquids mix; typically, an emulsifier for this purpose includes food-grade carrier oils, alcohols, and preservatives.