The passage of the 2018 United States Agriculture Improvement Act removed industrial hemp, defined as Cannabis sativa L. containing less than 0.3% THC content by dry weight, from Schedule I of the Controlled Substances Act and made it an agricultural commodity. Following these changes, the popularity of hemp-derived cannabidiol (CBD) dietary supplements by consumers has greatly exceeded the scientific understanding of purported benefits, safety and composition of these botanical extracts. Further complicating CBD hemp supplement regulation, Food and Drug Administration (FDA) considers CBD to be an approved drug (Epidiolex) in the treatment of severe epilepsy disorders, Dravet and Lennox-Gastaut syndromes. At the same time, hemp-derived CBD supplements can contain a complex phytochemical matrix from the hemp plant, distinguishing the composition of these products from isolated CBD preparations. This work aims to provide clarity on differentiating botanical full-spectrum hemp extracts containing CBD from isolates, from a phytochemical, toxicological and regulatory perspective.
Keywords: CBD; botanical extracts; cannabidiol; cannabis; dietary supplements; full-spectrum hemp extract; hemp.
While you might not know what to do with a pile of odorless CBD isolate powder at first, there are a number of different ways to consume CBD isolate. Here are some of the most common delivery routes:
While it’s true that hemp-derived CBD doesn’t have the same psychoactive effects as THC, that doesn’t mean it’s completely free of THC. According to federal law, hemp plants and hemp-derived products are legally permitted to contain up to 0.3% THC.
CBD crystalline can be measured and put into capsules or pills, allowing you to ingest an accurate dose. You can also mix CBD isolate with a variety of ingredients to create CBD-infused food and drinks. However, because CBD is not absorbed very well by the gastrointestinal tract, it has a low oral bioavailability. In order to increase bioavailability, CBD isolate can be added to carrier oils, such as MCT oil, to increase its chances of permeating the gastrointestinal system and reaching the bloodstream.
It’s incredibly easy to measure CBD isolate dosages, as there’s nothing else to account for aside from the pure CBD crystals.
CBD isolate can be mixed with terpenes to create homemade CBD concentrates that can be vaped or dabbed. The isolate can also be made into crystal slabs that can be dabbed using a traditional oil rig.
What is CBD isolate?
CBD is cannabidiol, a phytocannabinoid found in cannabis plants. CBD isolate is CBD that has been isolated from all other plant material through a process of extraction and refining. CBD isolate is available in crystal or powder form.
Apply the CBD powder directly under your tongue and hold it there for about 60 seconds. With this method, the CBD is absorbed by the mucous membranes and delivered directly to the bloodstream, bypassing the digestive system to provide more immediate and effective relief.