Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level of blood thinning and other medicines in your blood by competing for the liver enzymes that break down these drugs. Grapefruit has a similar effect with certain medicines.
CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot be sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other unknown elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
The evidence for cannabidiol health benefits
The Farm Bill removed all hemp-derived products, including CBD, from the Controlled Substances Act, which criminalizes the possession of drugs. In essence, this means that CBD is legal if it comes from hemp, but not if it comes from cannabis (marijuana) – even though it is the exact same molecule. Currently, many people obtain CBD online without a medical marijuana license, which is legal in most states.
People taking high doses of CBD may show abnormalities in liver related blood tests. Many non-prescription drugs, such as acetaminophen (Tylenol), have this same effect. So, you should let your doctor know if you are regularly using CBD.
How is cannabidiol different from marijuana, cannabis and hemp?
CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.
Outside of the US, the prescription drug Sativex, which uses CBD as an active ingredient, is approved for muscle spasticity associated with multiple sclerosis and for cancer pain. Within the US, Epidiolex is approved for certain types of epilepsy and tuberous sclerosis.
HDL helps remove LDL deposits and limits the buildup of plaque that leads to things like heart attack and stroke. If LDL levels are too high, plaque accumulation inside blood vessels can cause arteries to harden and become narrower. Plaque buildup can cause arteries to become fully blocked. A blocked artery prevents blood from reaching vital organs and tissues. The result is a heart attack or stroke.
Millions of Americans are currently using statins, and health experts suggest that millions more need to be using them. For example, the American College of Cardiology issued a set of recommendations for statins suggesting over 26 million Americans should be using them.
What Causes High Cholesterol?
If a doctor diagnoses you with high cholesterol, it’s likely they will recommend a medication known as a statin. Statins can help lower the risk of things like heart attack and stroke by over 30%.
In terms of medication for lowering cholesterol, it is common for physicians to prescribe statins. Statins inhibit an enzyme that the liver needs to produce LDL cholesterol. They also slightly increase HDL levels, which can move ‘bad’ cholesterol from the arteries to the liver.
There’s a problem with these recommendations…
Typically, your cholesterol level increases with age. There are a number of lifestyle choices that contribute to increased LDL cholesterol levels, such as smoking, being overweight, and eating too many saturated fats. Dietary culprits that typically lead to high cholesterol are dairy items, processed foods, and fatty red meats. A lack of physical activity can also negatively impact cholesterol levels. This is why many health experts suggest a minimum of 20 minutes of physical activity a day.