People taking high doses of CBD may show abnormalities in liver related blood tests. Many non-prescription drugs, such as acetaminophen (Tylenol), have this same effect. So, you should let your doctor know if you are regularly using CBD.
Animal studies, and self-reports or research in humans, suggest CBD may also help with:
A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot be sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other unknown elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.
Is CBD safe?
CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”
CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.
The evidence for cannabidiol health benefits
The Farm Bill removed all hemp-derived products, including CBD, from the Controlled Substances Act, which criminalizes the possession of drugs. In essence, this means that CBD is legal if it comes from hemp, but not if it comes from cannabis (marijuana) – even though it is the exact same molecule. Currently, many people obtain CBD online without a medical marijuana license, which is legal in most states.
Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer or COVID-19, which it is not. We need more research but CBD may prove to be a helpful, relatively non-toxic option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD currently is typically available as an unregulated supplement, it’s hard to know exactly what you are getting.
At the same time, not only do some products contain THC, a number of them had enough THC to cause symptoms like an increased heart rate. In this way, some CBD products can actually make anxiety worse.
This study found that CBD had no effect on anxiety, heart rate, or cortisol levels. Cortisol is known as a “fight or flight” hormone.
So far, most of the evidence linked to CBD’s effects on anxiety comes from animal studies and laboratory experiments. But it does show some promise.
Using CBD oil may cause a number of side effects. Ironically, one of these side effects can be anxiety. Others may include:
Cannabidiol is unlike tetrahydrocannabinol (THC). This other cannabis compound produces a “high.” CBD oil typically doesn’t contain THC, so it doesn’t have this effect.
For people dealing with pain, anxiety, or depression, taking CBD oil may seem like a quick and simple fix.
The uncertainty explains why it makes good sense to consult your healthcare provider before taking CBD oil. If your physician cannot recommend a brand, then he or she may be able to warn you off an irreputable brand.
Is CBD Legal?
If you were to plot this result on graph paper, it would form a bell, with 100 and 900 on the ends. Hence, the name of this pharmacology concept literally takes shape.
Their goal is clear, according to a survey published in Cannabis and Cannabinoid Research: Almost 62% of cannabidiol users say they use CBD to treat pain, anxiety, and depression.