Migraine is one of the world’s most prevalent neurological diseases, according to information from the Migraine Research Foundation, affecting approximately 39 million people in the U.S. and about one billion globally. Symptoms, which are often disabling, can include severe headache, dizziness, nausea, visual disturbances and severe sensitivity to light or sound. Migraine disease is commonly treated with strong pharmaceutical drugs, although with varying results.
The Axon CBD oil used in the migraine study.
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Although some research has shown that migraine sufferers report more relief from cannabis than they do from prescription medications, clinical studies that focus specifically on the effect that CBD can have on migraine are yet to be conducted. However, a 2018 study found that CBD, a non-intoxicating constituent of cannabis, has several pharmacological properties including acting as an anti-inflammatory, and anecdotal accounts of CBD oil successfully being used for migraine show promise.
Another participant in the study said that the CBD formulation “has significantly helped with my chronic migraines. If taken at onset, I can rely on it to take the edge off relatively quickly.”
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The survey was taken by customers using a CBD oil product designed by Axon Relief, a company that creates supplements specifically for migraine sufferers. Known as the Headache Impact Test (Hit-6), the clinically validated survey measures the impact that headaches have on a respondent’s daily life and ability to function.
Anyone considering the use of CBD oil for migraines should consult with their healthcare provider before taking it. It’s important to note that not all sources of the product are reputable.
Due to the pervasiveness and debilitating effects of migraine headaches, there’s been a lot of clinical research aimed at trying to find an effective treatment to minimize the frequency of migraines and alleviate the pain.
The researchers add that given time, as the legalities around medical marijuana and CBD oil change, more research may be able to show that CBD oil works well enough and consistently enough to treat migraines.
With the laws governing the legal use of medical marijuana beginning to loosen up, there’s quite a bit of focus on the use of CBD oil—a component of the marijuana plant—for treating everything from arthritis to chronic pain, including migraines. But what is CBD oil, and does it really work to relieve migraine headaches?
Uses and Safety
CBD oil has gotten a lot of attention for its powerful pain-relieving properties, particularly since cannabis use is becoming legal in many states (33 as of October 2019, according to the National Conference of State Legislatures, but details vary). In June 2018, the FDA approved CBD for the first time for a new seizure medication called Epidiolex (cannabidiol) [CBD] oral solution.
While few clinical research studies have examined the use of CBD to treat migraines, a 2016 study, published in Pharmacotherapy, found that the frequency of migraines was reduced from nearly 10 per month to only approximately four per month in a group of medical marijuana users. Research presented in 2017 at the Congress of the European Academy of Neurology showed that cannabinoids might help prevent migraines as well as easing the pain of migraine headache.
Another important action step to take before deciding to use CBD oil is to check to ensure that it is legal in your home state. Many states still consider even the prescribed use of CBD oil illegal, due to its link to marijuana. And the FDA has not approved any CBD products (prescription or over-the-counter), aside from Epidiolex.
Properties of CBD Oil That Relieve Migraine
According to a study published in Frontiers in Pharmacy, while there are many experts who advocate for the use of CBD oil for migraines, there is still not enough evidence to prove that treatment will CBD oil will be completely effective for alleviating migraine headaches.
Cannabidiol (CBD) is just one of over 100 different substances found in the the Cannabis sativa plant. The portion of the cannabis plant that produces a high (the psychotropic effect) is called tetrahydrocannabinol, or THC. Depending on how it’s processed, CBD oil contains very little (or is completely void of) THC.
Migraine headaches affect more than 38 million people within the US alone. Women are three times as likely to suffer from migraines as men.
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After failing with conventional treatment methods, many people desperately turn to natural resources for help — such as CBD oil.
Common Migraine Treatment Options
Since there’s no combustion, vaping CBD oil doesn’t deliver harmful substances to your system.
Aside from the unbearable pain, migraines can also trigger other symptoms such as nausea or vomiting, and sensitivity to light and sound.
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Anandamide (or AEA), one of several endocannabinoids produced by the human body, has the ability to both increase and decrease the activity of serotonin receptors. A paper from Neurology Letters suggests that this feature can have therapeutic applications within the domain of migraines. Anandamide has also been shown to be tonically active within the gray matter of the brain, which is responsible for migraine generation.
Research shows there’s a unique synergy between cannabinoids and terpenes which greatly increases their effects — this concept is known as the entourage effect. Simply put, the aforementioned compounds are more effective together than each of them in isolation.