It would be hard to overdose on CBD oil because human tolerance is very high. One study reported the toxic dose would be about 20,000 mg taken at one time.
The study also looked at stroke volume (the amount of blood remaining in the heart after a heartbeat). The stroke volume in the men who took CBD was lower than that in the placebo group, meaning the heart was pumping more efficiently.
Remember that CBD oils are mostly unregulated, so there's no guarantee that a product is safe, effective, or what it claims to be on its packaging.
The tricky part is calculating the exact amount of CBD per milliliter of oil. Some tinctures have concentrations of 1,500 mg per 30 mL, while others have 3,000 mg per mL (or more).
CBD oil is made from the leaves, stems, buds, and flowers of the Cannabis indica or Cannabis sativa plant and should contain less than 0.3% THC. Hemp oil is made from the seeds of Cannabis sativa and contains no TCH.
Some experts suggest CBD may help treat cannabis and nicotine dependence, but more research is needed.
Cytochrome P450 (CYP450) is an enzyme in your body that breaks down certain drugs. But CBD oil can block CYP450 from working the way it normally does. CBD oil can either make some drugs you take have a stronger effect than you need or make them less effective.
There aren't many study trials that look at CBD's anxiety-relieving effects in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry.
A 2015 review of studies in the journal Neurotherapeutics suggests that CBD might help treat anxiety disorders.
Andry points out that although 0.3% THC or less is recognized as legal, issues may arise with drug testing. “While 0.3% is not enough to cause any significant effect in the body, it could be enough to cause one to test positive on a drug test, obviously putting someone’s employment or legal status potentially at risk.”
Consumers should be aware that there is some inconsistency regarding CBD policies at a state level. Certain states still regard and police CBD as contraband rather than a health supplement if it contains THC. In states such as Idaho, Nebraska, and South Dakota, individuals possessing CBD products containing even the slightest concentration of THC may be charged with a felony.
“An oil that contains higher levels of alpha-pinene and limonene might make you feel more energetic or alert, while strains higher in linalool or myrcene might be more calming or sedating.”
CBD can be found in salves, drinks, gummies, and even sanitary products. However, its popularity means that there is misinformation about what CBD is, how it works, and if it’s even legal. If you’re unfamiliar with CBD but keen to learn more about its uses and benefits, read on.
Specifically, some of the conditions that CBD may benefit include:
“There’s variation from person to person,” Andry said. What is useful for some may not be so effective for others.
Andry also emphasized that dosage matters. CBD is a biphasic compound, which means that it causes distinct responses at different concentrations. At lower levels, CBD is energizing and increases wakefulness and alertness. At higher concentrations, it works as a sedative, causing the individual to feel sleepy and calm. In order to achieve the desired effects, it’s vital to talk to an expert at a dispensary or follow the dosage guidelines provided. A higher dose can be considered anywhere between 150 milligrams to 600 milligrams.
5. Is CBD oil legal?
Hemp-derived CBD oil is now legal under federal law following a provision of the 2018 Farm Bill which removed the federal ban on hemp production. To meet federal legal criteria, CBD oil must be made from hemp, the cannabis plant that contains no more than 0.3% THC.
There are also many anecdotal reports that CBD promotes feelings of drowsiness, helping those with insomnia to fall asleep and stay asleep. CBD also possesses anti-inflammatory properties and is an anxiolytic, which may also provide sleep aid by easing pain and anxiety.