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cbd oil indications

Cbd oil indications

Cytochrome P450 (CYP450) is an enzyme in your body that breaks down certain drugs. But CBD oil can block CYP450 from working the way it normally does. CBD oil can either make some drugs you take have a stronger effect than you need or make them less effective.

CBD oil comes in different forms. Isolates contain only CBD, but full-spectrum oils have several compounds from the cannabis plant. This includes proteins, flavonoids, terpenes, and chlorophyll.

However, there aren't many studies that examine the use of CBD in treating chronic pain in people. The studies that do exist almost always include THC. This makes it hard to isolate CBD's unique effects.

Dosage and Preparation

CBD oil might help people with substance use disorder, per a 2015 review in the journal Substance Abuse.

However, there’s no evidence CBD oil can treat high blood pressure on its own or prevent it in people at risk. While stress can complicate high blood pressure, it can’t cause it.

CBD oil may reduce the risk of heart disease by relieving high blood pressure in some people, per a 2017 study in JCI Insight.

What to Look For

There aren't many study trials that look at CBD's anxiety-relieving effects in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry.

A 2017 study reported that only 31% of CBD products sold online were correctly labeled. Most contained less CBD than advertised, while 21% had significant amounts of THC.

Cbd oil indications

Some CBD products may contain unwanted surprises. Forensic toxicologists at Virginia Commonwealth University examined nine e-liquids advertised as being 100 percent natural CBD extracts. They found one with dextromethorphan, or DXM, used in over-the counter cough medications and considered addictive when abused; and four with a synthetic cannabinoid, sometimes called Spice, that can cause anxiety, psychosis, tachycardia and death, according to a study last year in Forensic Science International.

This year, 1,090 people have contacted poison control centers about CBD, according to the American Association of Poison Control Centers. Over a third are estimated to have received medical attention, and 46 were admitted into a critical care unit, possibly because of exposure to other products, or drug interactions. In addition, concern over 318 animals poured into the American Society for the Prevention of Cruelty to Animals’ Animal Poison Control Center.

By Dawn MacKeen

A few drops of CBD oil in a mocha or smoothie are not likely to do anything, researchers contend. Doctors say another force may also be at play in people feeling good: the placebo effect. That’s when someone believes a drug is working and symptoms seem to improve.

Is CBD harmful?

While there is hope for treating other conditions with the plant extract, Epidiolex remains the only CBD-derived drug approved by the F.D.A. Most of the research on cannabidiol has been in animals, and its current popularity has outpaced science. “We don’t have the 101 course on CBD quite figured out yet,” said Ryan Vandrey, an associate professor of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine.

For students with generalized social anxiety, a four-minute talk, with minimal time to prepare, can be debilitating. Yet a small experiment in the journal Neuropsychopharmacology found that CBD seemed to reduce nervousness and cognitive impairment in patients with social anxiety in a simulated public speaking task.

Cannabidiol, or CBD, is the lesser-known child of the cannabis sativa plant; its more famous sibling, tetrahydrocannabinol, or THC, is the active ingredient in pot that catapults users’ “high.” With roots in Central Asia, the plant is believed to have been first used medicinally — or for rituals — around 750 B.C., though there are other estimates too.

Does CBD help sleep and depression?

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However, a double-blind study found healthy volunteers administered CBD had little to no change in their emotional reaction to unpleasant images or words, compared to the placebo group. “If it’s a calming drug, it should change their responses to the stimuli,” said Harriet de Wit, co-author of the study and a professor in the University of Chicago’s department of psychiatry and behavioral neuroscience. “But it didn’t.”