The associations between the predictor variables and fibrosis severity were analyzed with logistic regression. Separate models were developed to predict the odds of having mild fibrosis (F1–2) compared to no fibrosis (F0), excluding F3–F6, and the odds of having moderate to severe fibrosis (F3–6) compared to mild fibrosis (F1–2), excluding F0. Multivariate models were examined to estimate effects while controlling for important potential confounders. Predictor variables with a p-value ≤ 0.10 were evaluated in multivariate models. In multivariate models, biopsy adequacy, as measured by the number of portal tracts, was controlled for in all analyses. The analysis was performed using SAS statistical software version 9.1 (SAS Institute Inc., Cary, NC).
Subjects underwent an in-person interview that collected information about demographics, risk factors for HCV infection and use of cannabis, alcohol, and other substances. Interviewers and subjects were blinded to the hypothesis regarding cannabis use and fibrosis. Subjects were asked about the frequency of their current (within 12 months of enrollment) cannabis use. The response categories were everyday, three or four times a week, one or two times a week, seven to eleven times a month, one to three times a month, three to six times, twice, once or never in the last 12 months. Lifetime alcohol use was assessed in detail using a validated questionnaire (12). A standard drink was estimated to contain 10 grams of alcohol and was equivalent to 12 oz of beer, 1 oz liquor or 4 oz of wine. The duration, quantity, frequency and type (beer, liquor or wine) of alcohol consumed were recorded. Only 15.2% of subjects were aware of their liver biopsy results at the time of interview.
Hosmer-Lemeshow test, p=0.83
Complications of hepatitis C virus (HCV) infection are primarily related to the development of advanced fibrosis.
Predictors of Mild Fibrosis (F1–2) Compared to No Fibrosis (F0) – Univariate Analysis
Each person requires a specific and personalized dose determined by different health factors. The medical practitioner who checks a person’s health could offer advice on how much CBD is appropriate to use. Another way to identify the best dose is by experimenting. However, one should start with the lowest level of a dose.
To find out how to correctly dose your CBD, read our post on CBD dosage.
We recommend following the Step-Up method described in the book ” Patient’s Guide to Cannabis” by Leonard Leinow 6
Using CBD oil as a way of treating hepatitis has several benefits. CBD protects the liver from acute injury. A test done on mice 2 revealed the effect of treating hepatitis with CBD. The results showed a decrease in liver injury.
CBD Dosage For Hepatitis
Using CBD helps in breaking down these dangerous compounds that can react with crucial moles or DNA strands. When CBD binds with free radicals, it helps in preventing any damage that would arise from binding with important cell structures. Free radicals accumulate around the liver thus exerting pressure on the hepatic cells. Cannabinoids, therefore, act as a guard between the liver and the danger paused by the byproducts.
Autoimmune hepatitis (AIH) is a genetic, non-contagious, chronic inflammatory autoimmune disease in which the immune system attacks healthy, normal functioning liver cells. Hepatitis can cause liver cirrhosis, liver failure or even cancer.
Hepatitis is a condition defined by inflammation of the liver. The disease is mainly caused by a viral infection although there are other probable causes. Such include toxic substances, e.g., alcohol, drugs or medications and autoimmune diseases.
What Are The Side Effects of Using CBD to Treat Hepatitis?
CBD oil is consumed orally by putting drops underneath the tongue and holding it until it gets fully absorbed. It’s important not to swallow it right away, rather wait for it to be absorbed. This makes digestion and absorption much easier. You can also take it as capsules or mix it with a drink.
Infectious hepatitis which is contagious is primarily transmitted when an uninfected person ingests water or food that has been contaminated with feces of an infected individual. It can also be spread when blood or semen or any other body fluid from an infected person is passed to an uninfected individual. There are five types of this infection. Hepatitis D type occurs only when hepatitis B has been present.