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cbd oil alzheimer’s

Lewy body dementia (LBD) is a disease associated with abnormal deposits of a protein called alpha-synuclein in the brain. These deposits, called Lewy bodies, affect chemicals in the brain whose changes, in turn, can lead to problems with thinking, sleeping, movement, behavior, and mood. Unlike most pain, anxiety or behavior management drugs, CBD does not block acetylcholine, the main chemical that LBD attacks. Research has shown that CBD can be an effective anti-inflammatory agent, reduce motor symptoms (tremor, rigidity, bradykinesia) and maintain circadian (sleep) rhythms.

Frontotemporal dementia (FTD) or frontotemporal degenerations refers to a group of disorders caused by progressive nerve cell loss in the brain’s frontal lobes (the areas behind one’s forehead) or its temporal lobes (the regions behind one’s ears) that leads to symptoms of depression and psychosis. Unlike most antipsychotic drugs, CBD does not lead to an increased risk of death. Research has shown that CBD can be an effective anti-inflammatory agent, reduce anxiety, reduce motor symptoms (tremor, rigidity, bradykinesia) and maintain circadian (sleep) rhythms.

Parkinson’s Disease

The World Health Organization (WHO) stated that “no public health problems… have been associated with the use of pure CBD,” and there has been no known association with potential for dependence or abuse, unlike most pharma alternatives. The most commonly reported potential side effects of CBD usage were diarrhea and bloating, with some also reporting nausea. About 3% of patients in studies reported liver problems and had to discontinue CBD use. Specifically, in dementia, some patients reported increased tremor with high doses of CBD. As with any new treatment, patients and caregivers should monitor effects and outcomes closely.

Frontotemporal Dementia / Pick’s Disease

According to researchers at California’s Salk Institute, their 2016 study found evidence that cannabinoids such as CBD could help remove dementia from, and increase connections between, brain cells. Those results were validated by other laboratories. While the US Food and Drug Administration has yet to approve a CBD drug for the purposes of treating dementia, it has approved a CBD-based drug called Epidiolex for treating epilepsy.

Objective: To measure efficacy and safety of medical cannabis oil (MCO) containing THC as an add-on to pharmacotherapy, in relieving behavioral and psychological symptoms of dementia (BPSD).

Methods: Eleven AD patients were recruited to an open label, 4 weeks, prospective trial.

Results: Ten patients completed the trial. Significant reduction in CGI severity score (6.5 to 5.7; p < 0.01) and NPI score were recorded (44.4 to 12.8; p < 0.01). NPI domains of significant decrease were: Delusions, agitation/aggression, irritability, apathy, sleep and caregiver distress.

Background: Tetrahydrocannabinol (THC) is a potential treatment for Alzheimer’s disease (AD).

Cbd oil alzheimer's

Let’s start with the basics of CBD. It comes from the hemp plant , which is related to the marijuana plant . The plant is dried and the resin is extracted. This compound contains 2 parts: tetrahydrocannabinol (THC) and cannabidiol (CBD).

What Is CBD?

While this information gives us much hope in the fight against dementia, know that only small clinical trials have been conducted to determine the effects of CBD on dementia, making it difficult to come to a scientific conclusion. However, scientists are continuing to conduct rese arch to help further our ability to help those with dementia.

Oxygen Buildup

If you or your loved one is interested in using CBD to manage symptoms, make sure you talk to a doctor first to evaluate the risks and discuss the best options.