Also, cannabinoids can have side effects that are unpleasant or even harmful. It’s important to remember that the cannabinoids used in studies are made in a laboratory and are only one of many chemicals that are found in cannabis. Street-bought (recreational) cannabis contains chemicals that can cause you to hallucinate and could harm your mental health.
This is a topic people often call us about. Eating healthily, being physically active and staying a healthy weight is important for general health, but can be especially important for men with prostate cancer.
Q. Can cannabis help cure prostate cancer?
Why? Well, firstly because there’s strong evidence that being overweight increases the risk of aggressive or advanced prostate cancer.
It’s important to remember that it’s illegal to grow or sell cannabis in the UK. It’s also illegal to have any cannabis-based products, unless a doctor has prescribed them for medicinal use. CBD oil is legal, but only if it contains extremely low levels of THC (less than 0.2%). However, there’s little evidence to suggest CBD oil benefits cancer patients and there are still a lot of unanswered questions.
Q. Can changing my diet and keeping physically active help fight prostate cancer?
There’s some evidence that cannabis-based medicines can help with long-term pain, including pain caused by cancer. Currently doctors in the UK can only prescribe cannabis-based medicines to treat nausea or vomiting caused by chemotherapy – when other medicines haven’t worked. Cannabis-based medicines aren’t available to treat cancer-related pain unless you’re taking part in a clinical trial. If you’re interested, your doctor should be able to tell you about any clinical trials that might be suitable. You can also search for clinical trials at www.bepartofresearch.nihr.ac.uk
Medicinal cannabis must be distinguished from recreational cannabis which is used to achieve a psychotomimetic state of ‘high’. Cannabis strains used for recreational purposes contain a higher THC and lower CBD ratio than cannabis for medicinal use. Usually two cannabis plants are used: cannabis sativa which has a higher THC concentration and cannabis indica which has a higher CBD concentrate. The flavonoids are known for their antioxidant and anti-inflammatory effects. The terpenoids are resins (oil) with a strong odour.
These patients include those who have localised prostate cancer where active surveillance is followed, those with biochemical recurrence after treatment, and patients with metastatic PCa. I have always wondered whether cannabis oil could indeed be a cure for prostate cancer. Unfortunately, I do not see in practice the desired beneficial effect and the PSA values continue to rise. To find some answers, I did a search in scientific literature.
In the 1990s, the endocannabinoid system (ESC) of the body was discovered by Raphael Mechoulam, an Israeli professor of medical chemistry. The endocannabinoid system, a central regulatory system, is the body’s largest receptor system and is important to maintain the homeostasis of the body.
A challenge for the caregiver can be that the patient is convinced that we as healthcare practitioners work together with the pharmacists, and that we do not wish to carry out clinical trials (unfortunately, I hear that very often). We can hardly persuade patients that this is not true.
Studies on a certain CBD manufacturer showed its products were contaminated with a chemical known as 5F-ADB, which mimics THC. 5F-ADB is classified by the U.S. Drug Enforcement Administration as illegal, potentially addictive and with no accepted medical use.
This is very important for cancer patients to understand, as many people think CBD oil is not a medicine. They think of it more as a vitamin or a supplement, so they might not let their doctors know they’re using it. Patients might not realize it can be potentially harmful. So, it’s very important to tell your doctor if you’re using CBD oil.
Yes. Epidiolex. It was originally approved in 2018 for the treatment of two conditions, both related to epilepsy: Lennox-Gastaut syndrome and Dravet syndrome. But aside from Epidiolex, no CBD product has been approved by the FDA for any other medical purpose.
There have been reports that cannabinoids like THC and CBD may be helpful for nausea and vomiting and anorexia, as well as neuropathy, anxiety, depression and insomnia. Synthetic cannabinoids like dronabinol have been approved for use with chemotherapy-induced nausea and vomiting, but have not been shown to be superior to conventional anti-nausea medications.
Does CBD oil have any side effects?
There’s still a lot to learn. So always let your health care team know if you are using CBD oil. That way, we can make sure nothing interacts adversely with your cancer treatments or other medications.
In terms of purity, THC and CBD are both extracted from hemp and marijuana using essentially similar processes. But trace amounts of THC could still end up in CBD oil. And if the THC is at a high enough concentration, it could produce the psychoactive effects that THC is known for.