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The proliferation in the last few years of cannabidiol (CBD)-containing products in the U.S. markets has been greatly accelerated by changes in the regulatory environment, and by perceptions of their health benefits and presumed safety. The result has been aggressive marketing of many types of products, some of dubious quality, making or implying drug-type claims. The recent approval by the U.S. Food and Drug Administration (FDA) of CBD in the form of Epidiolex®, further complicates the regulatory picture. In addition, a number of studies suggest that, at least at high doses, there may be serious adverse effects or drug interactions associated with CBD. At present, CBD-containing products do not meet the strict definition of dietary supplements, but the FDA is continuing to consider some framework under which they might be allowed. Meanwhile, FDA has adopted a “risk-based” enforcement policy. Possible approaches to a new framework for regulation of CBD products as dietary supplements are discussed here, including expanded research emphasis, a robust corporate stewardship program, and a rigorous adverse event reporting program.

Keywords: Cannabidiol; dietary supplements; regulations.

When it comes to the brain, THCV also shows some promise. A 2010 study published in Epilepsia showed that THCV may be able to reduce the frequency and severity of seizures related to epilepsy, even working as a potential preventative measure. There isn’t yet, however, any relevant research tied to stress reduction or relief.

While CBD products claim to offer relief from everything to stress to aches and pains to inflammation, THCV is a little different. This highly-hyped compound comes with claims that it can suppress your appetite and help you lose weight. But can this cannabinoid really have an impact on your hunger?

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It’s important to note that Delta Nine THCV isn’t the same as the Delta Eight variety. While the two seem to share the same name, Delta Eight doesn’t make the same health claims as Delta Nine. So, when you’re talking about THCV, it’s a good idea to double-check whether the product in question is the Delta Eight or Delta Nine variety (here, we’re talking about Delta Nine only).

Photo: Erin Scott

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But what, really, is THCV? It’s one of the many cannabinoids found in cannabis plants, and Delta 9 THCV was first discovered in the 1970s . Unlike THC and CBD, which are byproducts of cannabigerolic acid (CBGA), THCV is a byproduct of cannbigerovarin acid (CBGVA). The CBGVA turns into THCVA, and when it’s exposed to heat or light, it ultimately becomes THCV.

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