Cannabidiol, or CBD, is one of over a 100 different types of a specific kind of compound called phytocannabinoids found in the Cannabis sativa plant.
It is estimated that the CYP system is responsible for metabolizing over 60% percent of any drug that has been consumed. And interestingly, pharmaceutical researchers and doctors also use cytochrome P450 system to understand, calculate and predict drug dosages effects as well as its potential side effects.
CBD And The Cytochrome P450 System
As mentioned, and contrary to popular belief and anecdotal evidence, CBD is not a biologically inert compound. Rather, CBD has a complex pharmacokinetic and pharmacodynamic profile similar to any other medication, and has the potential to interact with other medications and medical conditions.
Moreover, it isn’t recommended to be used in children with influenza or the common cold, as it can result in the development of a nearly fatal, progressive brain disease known as Reye’s Syndrome. The use of this medication is contraindicated to patients on warfarin treatment or those with disorders affecting the lining of the stomach such as peptic ulcers and gastritis. The medication should not be taken with alcohol.
Aspirin is a widely available, over-the-counter medication that is used by almost all age groups. However, it’s crucial to keep in mind the fact that there are several side effects of this medication that need to be considered.
Based on the effect of CBD on the main drug, the CBD-drug interactions can be classified into three types:
Adverse Effects of Aspirin
However, with higher doses or long-term use, CBD could, theoretically, increase serum levels of Aspirin over time — leading to potential side effects.
CBD increases the effect of the drug by exerting the same effects. This is common in drugs that share similar painkilling, sedative, anxiolytic, or anti-inflammatory effects.
Some of the common side effects of Aspirin include:
What Does Aspirin Do?
It’s widely prescribed to patients with cardiac disorders such as heart attack, heart failure, or cardiac arrests as a blood thinner that will prevent any blood clots from forming, and consequently, producing a cardiac injury.
Aspirin, and its generic component acetylsalicylic acid (ASA). It’s a medication commonly used for the treatment of pain, inflammation, and fever. It’s classified as a non-steroidal anti-inflammatory drug — NSAIDs for short.