No research has explicitly documented interactions between Xanax and CBD. Patients taking Xanax who are interested in CBD should speak to their healthcare providers for more information.
No studies have examined potential interactions between CBD and metoprolol. However, some placebo-controlled research conducted on healthy people at the University of Nottingham in England and published in 2017 in the journal JCI Insight has linked CBD with decreased blood pressure when taken on its own. For patients taking metoprolol, however, the combination with CBD could potentially have negative impacts on blood pressure.
No research conclusively warns patients against taking these drugs with CBD, though the previously cited 2013 study published in the Canadian Medical Association Journal has shown that grapefruit and drug interactions can lead to severe effects, including irregular heartbeat and sudden death, kidney failure, and muscle damage. Every patient’s case is unique, and individuals should speak to their healthcare providers if they are considering taking CBD in combination with particular prescription medications.
Clobazam, used to treat epileptic seizures, is another type of drug that may not be advisable to take in conjunction with CBD. However, Epidiolex is an FDA-approved, CBD-based drug that physicians may prescribe to treat epilepsy. A significant amount of data, derived from clinical trials, exists on Epidiolex, although the drug can also cause adverse effects, according to a 2019 study conducted by researchers at Columbia University and published in the journal F1000Research.
Should I take CBD with statins?
Let’s examine the current research on CBD’s interaction with several common prescription and over-the-counter medications.
According to a 2011 study published in the journal Life Sciences, it is possible that CBD has an inhibitory effect on CYP2C19, the enzyme that metabolizes Plavix. This could cause Plavix to remain longer in the body and weaken its overall effects. Further research is required to determine whether this could lower Plavix’s effectiveness in preventing heart attacks.
Patients taking metoprolol or other beta-blockers should consult their doctor as to whether to consume CBD.
Should I take CBD with metoprolol?
Cannabis is a complex plant, with hundreds of chemicals and over 100 distinct cannabinoids. The little research that examines cannabidiol or CBD, the second most common cannabinoid found in cannabis, shows evidence of potential health benefits for a wide range of conditions. As CBD becomes more mainstream, however, a key question comes to mind, “How will CBD interact with my current medication?”
Acetaminophen and CBD both are metabolized by CYP450, which lowers the effectiveness of both chemicals as they’re processed in the body. One controversial 2019 study, conducted by the University of Arkansas on mice and published in the journal Molecules, claimed that high doses of CBD contributed to liver toxicity, which could compound acetaminophen’s liver damage potential. However, the study’s authors have been accused of cherry-picking research and designing experiments to showcase potential CBD toxicity. The one study they cited with human test subjects did not show liver toxicity from CBD.
While there are many different types of anticoagulants, Warfarin is the most commonly prescribed. Warfarin is metabolized (processed through your body) by the hepatic P450 enzyme system. CBD and Warfarin both act on similar proteins in this enzyme system which can cause the warfarin to not be processed as effectively by the body. CBD is not a strong blood thinner, however, it acts on the same systems that blood thinners do. This means that CBD may contribute to additional blood thinning when taken in conjunction with other anticoagulants such as Warfarin. As such, taking both medications can increase the risk of bleeding complications. While Warfarin normally decreases the risk of blood clots, too much of an anticoagulant can cause serious bleeding. Your blood can not clot effectively enough leading to an increased risk of excessive bleeding.
If your doctor knows that you using CBD products, you will be able to get tips and information about the possible drug interactions or side effects. They may decide to monitor your blood closely or advise against taking CBD oil at the same time as your other medication.
What are the different types of blood thinners?
Aspirin is an incredibly common antiplatelet drug. Once again, CBD acts on the cytochrome P450 enzyme system in your body. This system, found within the liver, is responsible for metabolizing (breaking down) potentially toxic compounds, including over 60% of any drugs consumed. When this system is processing more than it is used to, it can metabolize substances differently than it normally would. As such, taking CBD with other medications that act on this system can cause unexpected effects.
Many patients wonder whether taking CBD oil (also known as hemp oil) in parallel with their medications can cause negative drug interactions. Luckily, studies have been done in the past, and are currently ongoing, concerning how CBD affects the body in conjunction with other medications. While CBD oil is normally safe, it can cause some side effects, especially if taken in large amounts or improper dosages. Since CBD oil can interact with certain foods and beverages (such as mangos and coffee), it can also interact either positively or negatively with certain medications – such as blood thinners. Therefore, it is important to know how CBD oil can interact with your medicines before taking them together. This article will share useful information about CBD oil and drug interactions so you can make the best decisions for your health. It is essential to consult with your doctor for personalized medical advice about every drug you use, including any over the counter medications, when starting new prescription medications.
How do you safely take both CBD and other medications?
However, there is another way to determine if CBD oil and your other prescription will likely interact negatively in your body – the grapefruit test. One of the components of grapefruit interferes with the cytochrome p450 enzymes – and so does CBD oil. If your doctor recommends you avoid grapefruit or grapefruit juice during your treatment, you should likely avoid hemp oil as well.