She pointed out that CBD does not cause a high, as THC does, which makes the drug more useful.
The university says that the researchers looked at how the proteins from the genome operated in human kidney cells and healthy control cells, both with and without CBD.
Maria Fernandes, who performed the cell studies, said, “This suggests CBD at the right dose could help cells be in a better state of readiness to respond to a virus, but it doesn’t cause a response unless there is a need.”
The University of Waterloo says that the study, Cannabidiol and the anti-viral response to SARS-CoV-2 proteins, showed that the non-psychoactive compound, which is also found in the cannabis plant, “appears to prime the innate immune system of cells, potentially offering protection against pathogens such as SARS-CoV-2.”
“They do this by activating innate responses inside of cells, which form the first line of defence. In the case of COVID-19, however, this response isn’t very good, which has contributed to high infection rates.”
“This could stop an infection, or slow its spread in the body or to others,” Duncan explained.
She went on to note that in cells that had not been previously exposed to the coronavirus, therapeutic amounts of CBD seemed to increase the cells’ preparedness to respond to viral infections.
The school says its researchers discovered that CBD increases the cell’s response to several key proteins produced by the coronavirus genome. It says the effect had not been discovered prior to the study.
Duncan pointed to a U.S. study to back her own, noting that it showed that epilepsy patients who used a high-dose pharmaceutical CBD had around a 10-fold lower risk of testing positive for COVID-19.
Inhibit of SARS-CoV2/COVID19 transmission: Authors purpose C.sativa extract mouth wash as a preventative treatment to be carried out at home.
Enas Abushah, David Ahern, Jennifer Alderson, Hannah Almuttaqi, Dominic Alonzi, Aljawharah Alrubayyi, Ghada Alsaleh, Tharini Askumar, Vicky Batchelor, Dorothee Berthold, Tehmina Bharucha, Henry Blest, Helene Borrmann, Mariana Borsa, Rowie Borst, Juliane Brun, Athena Cavounidis, Pablo Cespedes, Anne Chauveau, Lise Chauveau, Liliana Cifuentes Gutierrez, Jennifer Cole, Isabella Collins, Laura Collins, Ewoud Compeer, Clarissa Coveney, Amy Cross, Sara Danielli, Linnea Drexhage, Arthur Dyer, Fabian Fischer, Anis Gammage, Lee Garner, Ester Gea-Mallorqui, Valentina Gifford, Maria Gomez Vazquez, Cornelia Heuberger, Alina Janney, Kathrin Jansen, Rebecca Jeffery, Elizabeth Jennings, Stuart Keppie, Fangfang Lu, Iona Manley, Elizabeth Mann, Anna Marzeda, Julie Mazet, Linda Mies, Hayat Muhammad, Miriam O’Hanlon, Zahra Oubihi, Sumeet Pandey, Clara Pavillet, Claire Pearson, Garbiela Pirgova, Max Quastel, Niamh Richmond, Felix Richter, Rachel Rigby, Alice Robinson, Arvind Sami, Raphael Sanches Peres, Barbora Schonfeldova, Cariad Shorten,Michael Tellier, Emily Thornton, Lion Uhl, Erinke Van Grinsven, Lihui Wang, Joseph Wilson, Isaac Wong, Shamsideen Yusuf, Kristina Zec, Dingxi Zhou, Amanda Zhu
· Identification of 13 high-Cannabinoid cannabidiol (CBD) C.sativa extracts that modulate ACE2 gene expression and protein levels in artificial 3D models of oral, airway and intestinal human tissues.
HUGE THANKS TO THE FOLLOWING OXFORD STUDENTS AND POST-DOCS WHO HAVE BEEN REVIEWING THESE ARTICLES;
Appropriate statistics: No. Only 2 samples used in the majority of this paper for each group. Therefore, students t-test is likely not possible.