Another compromise is broad-spectrum CBD, which is essentially full-spectrum minus the THC. These products are more difficult to come by, but they are steadily becoming available from an increasing number of manufacturers.
However, sometimes the immune system can become overactive and generate inflammation for no apparent reason. This leads to a variety of painful conditions, including ankylosing spondylitis. It appears that this is where cannabinoids like THC and CBD can help. They dampen immune system activity and reduce inflammation and pain.
The symptoms of ankylosing spondylitis can range from mild to disabling. Some patients experience back pain that comes and goes and may even improve over time. However, for others, the disease follows a more progressive course.
As the body tries to compensate, it generates new bone, causing the vertebrae to fuse. This leads to a loss of flexibility and mobility, known as ankylosis. It can also affect the ribs and cause breathing problems.
Full-Spectrum vs. CBD Isolate
One such study appeared in the European Journal of Pain in 2016. Its authors investigated the effects of transdermal CBD on rats with inflammation due to arthritis. They massaged CBD gel into the rats’ skin for four days. At the end of this timeframe, the rats showed reductions in joint swelling and pain.
A more recent 2019 study for Postgraduate Medicine found that CBD also benefits humans living with chronic pain. It included 97 participants with painful conditions who had been using opioids for at least one year.
However, full-spectrum products do contain trace levels of THC. Although it is not enough to cause intoxication, it may cause some people concern. In this case, CBD isolate may be the solution.
Does CBD Help Ankylosing Spondylitis?
Understand the difference!…
The downside of oral CBD consumption is that it has a low bioavailability rate. This means that much of the active ingredient is lost in the metabolization process.
CBD topicals come as lotions, ointments, creams, and balms and are applied directly to the skin where pain relief is desired. Ointments, salves, and balms tend to require fewer applications than lotions and creams. Some early research has shown that topical applications can have better absorption rates than oral rates. Apply generously and frequently for pain relief.
CBD is a potent anti-inflammatory that inhibits cell proliferation, which basically means the cell production and division that are responsible for the excessive build-up of bone tissue in the vertebrae.
Ankylosing spondylitis is a type of spinal arthritis and an autoimmune disease. As with rheumatoid arthritis, AS pain is an overactive inflammatory response to the disease itself, which leads to damage to healthy tissue. Over time, AS can cause vertebrae to fuse, leading to the distinctive hunched posture, and loss of spinal flexibility. It can even affect the ribcage, leading to difficulty in breathing deeply.
AS occurs more often in men than women, with symptoms beginning in adulthood (17 – 45). However, onset has been noted in children and the elderly.
CBD for ankylosing spondylitis
Because AS is an autoimmune disease, it begins at a cellular level, and that is where CBD is at its most helpful. In simple terms, CBD calms the immune response and helps to lessen pain and inflammation.
The National Institutes of Health sponsored an investigation into CBD’s role in reducing chronic pain and inflammation. The research has shown that CBD’s anti-oxidative and anti-inflammatory properties were instrumental in reducing chronic pain. CBD acts on your body’s CB1 receptors to mute the pain signal to the brain through the cellular mechanisms outlined above.
Usually, it takes time and experimentation to find an effective dose. Most new users begin with two 5 mg doses, taken morning and evening. Every 7 – 10 days, increase each dose by about half until pain relief is effective.
What is ankylosing spondylitis?
Treatment for ankylosing spondylitis involves a multi-pronged approach of medication, exercise, and physical therapy. NSAIDs are usually the first line recourse for the management of pain and inflammation. The potential side effects of NSAIDs have been noted above. Practicing good posture and the application of hot/cold packs are other treatment options.
Cannabidiol agonist activity (initiation of a physiological response, combined with a receptor) at CB2 receptors appears to be responsible for its anti-inflammatory properties and its influence on pain perception. Initial human and animal studies support the premise that CBD reduces chronic pain and inflammation.